Spermatozoa from mice deficient in Niemann-Pick disease type C2 (NPC2) protein have defective cholesterol content and reduced in vitro fertilising ability

Busso D, Oñate-Alvarado MJ, Balboa E, Castro J, Lizama C, Morales G, Vargas S, Härtel S, Moreno RD and S ZanlungoReproduction, Fertility and Development, 26(4), 609-21. doi: 10.1071/RD12059 ABSTRACTThe cholesterol content of the sperm membrane…

Ryanodine receptor-mediated Ca2+ release underlies iron-induced mitochondrial fission and stimulates mitochondrial Ca2+ uptake in primary hippocampal neurons

San Martín CD, Paula-Lima AC, García A, Härtel S, Núñez MT and C HidalgoFrontiers in Molecular Neuroscience, 11, 7-13. doi: 10.3389/fnmol.2014.00013 ABSTRACTMounting evidence indicates that iron accumulation impairs brain function. We have reported previously that…