PUBLICATIONS
2024
Human-in-the-Loop—A Deep Learning Strategy in Combinationwith a Patient-Specific Gaussian Mixture Model Leads to the FastCharacterization of Volumetric Ground-Glass Opacity andConsolidation in the Computed Tomography Scans ofCOVID-19 Patients
Journal of Clinical Medicine, 2024, 13, 5231. The accurate quantification of ground-glass opacities (GGOs) and consolidation volumes has prognostic value in COVID-19 patients. Nevertheless, the accurate manual quantification of the corresponding volumes remains a time-consuming…
Proteus mirabilis biofilm expansion microscopy yields over 4-fold magnification for super-resolution of biofilm structure and subcellular DNA organization.
Castagnini, D., Palma, K., Jara-Wilde, J., Navarro, M. N., González, M. J., Toledo, J., … & Härtel, S. (2024). Proteus mirabilis biofilm expansion microscopy yields over 4-fold magnification for super-resolution of biofilm structure and subcellular DNA organization. Journal of Microbiological Methods, 106927.
E-Learning Module for Cytopathology Education Based on Virtual Microscopy
Cubillos, P., Diaz, E., Báez, P., Gutiérrez, L., Molina, C., & Härtel, S. (2023). E-Learning Module for Cytopathology Education Based on Virtual Microscopy. Journal of the American Society of Cytopathology.
2023
Strengthening Community Governance in Latin American Bioimaging Network
Olivera, A., Pietrasanta, L., Kamaid, A., Miranda, K., Carvalho, H., Hartel, S., … & Casanova, G. (2023, August). Strengthening Community Governance in Latin American Bioimaging Network. In Open Infrastructure Fund/Fondo de Infraestructura Abierta.
Amyloid β-Oligomers Inhibit the Nuclear Ca2+ Signals and the Neuroprotective Gene Expression Induced by Gabazine in Hippocampal Neurons
Lobos, P., Vega-Vásquez, I., Bruna, B., Gleitze, S., Toledo, J., Härtel, S., … & Paula-Lima, A. (2023). Amyloid β-Oligomers Inhibit the Nuclear Ca2+ Signals and the Neuroprotective Gene Expression Induced by Gabazine in Hippocampal Neurons. Antioxidants, 12(11), 1972.
VolumePeeler: a novel FIJI plugin for geometric tissue peeling to improve visualization and quantification of 3D image stacks
Gatica, M., Navarro, C. F., Lavado, A., Reig, G., Pulgar, E., Llanos, P., … & Cerda, M. (2023). VolumePeeler: a novel FIJI plugin for geometric tissue peeling to improve visualization and quantification of 3D image stacks. BMC bioinformatics, 24(1), 1-7
CNN Stability Training improves robustness to scanner and IHC-based image variability for epithelium segmentation in cervical histology
Miranda Ruiz, F., Lahrmann, B., Bartels, L., Krauthoff, A., Keil, A., Tao, A. S., … & Grabe, N. CNN Stability Training improves robustness to scanner and IHC-based image variability for epithelium segmentation in cervical histology. Frontiers in Medicine, 10, 1173616.
Detection of intermuscular coordination based on the causality of empirical mode decomposition
Cruz-Montecinos, C., García-Massó, X., Maas, H., Cerda, M., Ruiz-del-Solar, J., & Tapia, C. (2023). Detection of intermuscular coordination based on the causality of empirical mode decomposition. Medical & Biological Engineering & Computing, 61(2), 497-509.
The limitations and challenges in the assessment of executive dysfunction associated with real-world functioning: The opportunity of serious games
Martínez-Pernía, D., Olavarría, L., Fernández-Manjón, B., Cabello, V., Henríquez, F., Robert, P., … & Slachevsky, A. (2023). The limitations and challenges in the assessment of executive dysfunction associated with real-world functioning: The opportunity of serious games. Applied Neuropsychology: Adult, 1-17.
A computational framework for testing hypotheses of the minimal mechanical requirements for cell aggregation using early annual killifish embryogenesis as a model
Montenegro-Rojas, I., Yañez, G., Skog, E., Guerrero-Calvo, O., Andaur-Lobos, M., Dolfi, L., … & Rudge, T. J. (2023). A computational framework for testing hypotheses of the minimal mechanical requirements for cell aggregation using early annual killifish embryogenesis as a model. Frontiers in Cell and Developmental Biology, 11, 959611.
Diagnóstico Integral para el Desarrollo de Competencias en Salud Digital en la Red de Salud Digital de Universidades del Estado RSDUE
Gutiérrez S., Härtel S., Molina M., Campos R., Carvajal A., Salinas A., Bravo F., Agudelo MF., González E., Ramírez T., Cardona M., Cáceres S., Castro P., Ulloa V., López J., Guiñez S., Coñuecar S., Arancibia C. Universidad de Chile. Diagnóstico Integral para el Desarrollo de Competencias en Salud Digital en la Red de Salud Digital de Universidades del Estado RSDUE
Role of Proteus mirabilis flagella in biofilm formation
Scavone, P., Iribarnegaray, V., González, M. J., Navarro, N., Caneles-Huerta, N., Jara-Wilde, J., … & Zunino, P. (2023). Role of Proteus mirabilis flagella in biofilm formation. Revista Argentina de Microbiología.
2022
Automatic language analysis identifies and predicts schizophrenia in first-episode of psychosis
Figueroa-Barra, A., Del Aguila, D., Cerda, M., Gaspar, P. A., Terissi, L. D., Durán, M., & Valderrama, C. (2022). Automatic language analysis identifies and predicts schizophrenia in first-episode of psychosis. Schizophrenia, 8(1), 53.
Palmitic acid control of ciliogenesis modulates insulin signaling in hypothalamic neurons through an autophagy-dependent mechanism
Ávalos, Y., Hernández-Cáceres, M. P., Lagos, P., Pinto-Nuñez, D., Rivera, P., Burgos, P., … & Morselli, E. (2022). Palmitic acid control of ciliogenesis modulates insulin signaling in hypothalamic neurons through an autophagy-dependent mechanism. Cell Death & Disease, 13(7), 659.
Geometrical characterization of active contraction pulses in epithelial cells using the two-dimensional vertex model
Pérez-Verdugo, F., Reig, G., Cerda, M., Concha, M. L., & Soto, R. (2022). Geometrical characterization of active contraction pulses in epithelial cells using the two-dimensional vertex model. Journal of the Royal Society Interface, 19(186), 20210851.
Ethnicity influences phenotype and clinical outcomes: Comparing a South American with a North American inflammatory bowel disease cohort
Pérez-Jeldres, T., Pizarro, B., Ascui, G., Orellana, M., Cerda-Villablanca, M., Alvares, D., … & Tobar, F. (2022). Ethnicity influences phenotype and clinical outcomes: Comparing a South American with a North American inflammatory bowel disease cohort. Medicine, 101(36), e30216.
Diversification of habenular organization and asymmetries in teleosts: Insights from the Atlantic salmon and European eel
Michel, L., Palma, K., Cerda, M., Lagadec, R., Mayeur, H., Fuentès, M., … & Mazan, S. (2022). Diversification of habenular organization and asymmetries in teleosts: Insights from the Atlantic salmon and European eel. Frontiers in Cell and Developmental Biology, 10.
The Transcriptomic Portrait of Locally Advanced Breast Cancer and Its Prognostic Value in a Multi-Country Cohort of Latin American Patients
Llera, A. S., Abdelhay, E. S. F. W., Artagaveytia, N., Daneri-Navarro, A., Müller, B., Velazquez, C., … & Flaks, D. (2022). The transcriptomic portrait of locally advanced breast cancer and its prognostic value in a multi-country cohort of Latin American patients. Frontiers in oncology, 12, 836.
Ontogenesis of the asymmetric parapineal organ in the zebrafish epithalamus
Palma, K., Signore, I. A., Meynard, M. M., Ibarra, J., Armijo-Weingart, L., Cayuleo, M., … & Concha, M. L. (2022). Ontogenesis of the asymmetric parapineal organ in the zebrafish epithalamus. Frontiers in Cell and Developmental Biology, 10.
Socioeconomic, Clinical, and Molecular Features of Breast Cancer Influence Overall Survival of Latin American Women
De Almeida, L. M., Cortes, S., Vilensky, M., Valenzuela, O., Cortes-Sanabria, L., de Souza, M., … & Garbovesky, C. (2022). Socioeconomic, clinical, and molecular features of breast cancer influence overall survival of Latin American women. Frontiers in Oncology, 12, 556.
Gliovascular alterations in sporadic and familial Alzheimer’s disease: APOE3 Christchurch homozygote glioprotection
Henao‐Restrepo, J., López‐Murillo, C., Valderrama‐Carmona, P., Orozco‐Santa, N., Gomez, J., Gutiérrez‐Vargas, J., … & Posada‐Duque, R. (2022). Gliovascular alterations in sporadic and familial Alzheimer’s disease: APOE3 Christchurch homozygote glioprotection. Brain Pathology, e13119.
Datos de interés público para informar, tomar decisiones y crear conocimiento
Araos R, Basso L, Bravo L, Escobar MJ, Etcheverry A, Härtel S, Hermosilla MP, Jara A, Maass A, Marquet P and Pérez-Acle T (2022). Datos de interés público para informar, tomar decisiones y crear conocimiento. Comité Asesor Ministerial de Datos de Interés Público – MinCiencia
The Dendritic Ergic: Microtubule And Actin Cytoskeletons Participate In Stop‐And‐Go Movement Of Mobile Carriers Between Stable Structures
de los Ángeles Juricic Urzúa, M., Rojas, J. G., Correa, A. C., Cerda, M., Gründler, S. H., & González‐Silva, C. (2022). The dendritic ERGIC: Microtubule and actin cytoskeletons participate in stop‐and‐go movement of mobile carriers between stable structures. Traffic, 23(3), 174-187.
2021
Junctional ER Organization Affects Mechanotransduction at Cadherin-Mediated Adhesions
Joy-Immediato, M., Ramirez, M. J., Cerda, M., Toyama, Y., Ravasio, A., Kanchanawong, P., & Bertocchi, C. (2021). Junctional ER Organization Affects Mechanotransduction at Cadherin-Mediated Adhesions. Frontiers in Cell and Developmental Biology, 9, 669086.
Modular reorganization of gait in chronic but not in artificial knee joint constraint
Cruz-Montecinos, C., Pérez-Alenda, S., Cerda, M., & Maas, H. (2021). Modular reorganization of gait in chronic but not in artificial knee joint constraint. Journal of Neurophysiology, 126(2), 516-531.
Perioperative chemotherapy in locally advanced gastric cancer in Chile: from evidence to daily practice
Müller, B., García, C., Sola, J. A., Fernandez, W., Werner, P., Cerda, M., … & Corvalan, A. H. (2021). Perioperative chemotherapy in locally advanced gastric cancer in Chile: from evidence to daily practice. ecancermedicalscience, 15.
Qualitative ultrasonography scale of the intensity of local twitch response during dry needling and its association with modified joint range of motion: a cross-sectional study
Cruz-Montecinos, C., Cerda, M., Becerra, P., Tapia, C., Núñez-Cortés, R., Latorre-García, R., … & Cuesta-Vargas, A. (2021). Qualitative ultrasonography scale of the intensity of local twitch response during dry needling and its association with modified joint range of motion: a cross-sectional study. BMC Musculoskeletal Disorders, 22(1), 1-9.
B Cells Adapt Their Nuclear Morphology to Organize the Immune Synapse and Facilitate Antigen Extraction
Ulloa, R., Corrales, O., Cabrera-Reyes, F., Jara-Wilde, J., Saez, J. J., Rivas, C., … & Diaz-Muñoz, J. (2021). B Cells Adapt Their Nuclear Morphology to Organize the Immune Synapse and Facilitate Antigen Extraction. Frontiers in Immunology, 12, 801164-801164.
Mesa técnica “Fondo de Salud Extraordinario: Propuestas de Universidades, Sociedades Científicas y Colegios Profesionales”
Álvarez Román, F.; Araya Saldivar, L.; Varas Rocco, M.; Arribada Maldonado, A.,….Lampert Grassi, MP. (2021). Mesa técnica “Fondo de salud extraordinario : Propuestas de Universidades, Sociedades Científicas y Colegios Profesionales”. Biblioteca del Congreso Nacional de Chile, pp. 245-263.
Apical contacts stemming from incomplete delamination guide progenitor cell allocation through a dragging mechanism
Pulgar E., Schwayer C., Guerrero N., López L., Márquez S, Härtel S., Soto R., Heisenberg CP. And ML Concha (2021) Apical contacts stemming from incomplete delamination guide progenitor cell allocation through a dragging mechanism. eLife 10:e66483
Content‐Based Medical Image Retrieval and Intelligent Interactive Visual Browser for Medical Education, Research and Care
Sotomayor C., Mendoza M., Castañeda V., Farías H., Molina G., Pereira G., Härtel S., Solar M., Araya M. (2021). Content‐Based Medical Image Retrieval and Intelligent Interactive Visual Browser for Medical Education, Research and Care. Diagnostics 2021, 11, 1470.
Ryanodine receptor-mediated Ca2+ release and atlastin-2 GTPase activity contribute to IP3-induced dendritic Ca2+ signals in primary hippocampal neurons
Ramírez, O. A., Córdova, A., Cerda, M., Lobos, P., Härtel, S., Couve, A., & Hidalgo, C. (2021). Ryanodine receptor-mediated Ca2+ release and atlastin-2 GTPase activity contribute to IP3-induced dendritic Ca2+ signals in primary hippocampal neurons. Cell Calcium, 96, 102399.
A global view of standards for open image data formats and repositories.
Swedlow, J.R., Kankaanpää, P., Sarkans, U. et al. A global view of standards for open image data formats and repositories. Nat Methods (2021).
The incidence of psoriasis in Chile: an analysis of the national Waiting List Repository.
Lecaros, C., Dunstan, J., Villena, F., Ashcroft, D. M., Parisi, R., Griffiths, C. E. M., … & De la Cruz, C. (2021). The incidence of psoriasis in Chile: an analysis of the national Waiting List Repository. Clinical and Experimental Dermatology.
RyR-mediated Ca2+ Release Induced by Neuronal Stimulation Participates in Nuclear Ca2+ Signal Generation, CREB Phosphorylation and Npas4 Expression.
Lobos, P., Córdova, A., Vega-Vásquez, I., Ramírez, O. A., Adasme, T., Toledo, J., … & Hidalgo, C. (2021). RyR-mediated Ca2+ release elicited by neuronal activity induces nuclear Ca2+ signals, CREB phosphorylation, and Npas4/RyR2 expression. Proceedings of the National Academy of Sciences, 118(33).
Salmonella Typhimurium Triggers Extracellular Traps release in Murine Macrophages.
Mónaco, A., Canales-Huerta, N., Jara-Wilde, J., Härtel, S., Chabalgoity, J. A., Moreno, M., & Scavone, P. (2021). Salmonella Typhimurium triggers Extracellular Traps release in murine macrophages. Frontiers in cellular and infection microbiology, 11.
Zebrafish Neural Crest: Lessons and Tools to Study In Vivo Cell Migration.
Alhashem, Z., Portillo, M. A. G., Htun, M. R., Gauert, A., Montecinos, L. B., Härtel, S., & Linker, C. (2021). Zebrafish Neural Crest: Lessons and Tools to Study In Vivo Cell Migration. In The Epithelial-to Mesenchymal Transition (pp. 79-106). Humana, New York, NY.
2020
Exergames and telerehabilitation on smartphones to improve balance in stroke patients
Burgos, P. I., Lara, O., Lavado, A., Rojas-Sepúlveda, I., Delgado, C., Bravo, E., … & Cerda, M. (2020). Exergames and telerehabilitation on smartphones to improve balance in stroke patients. Brain Sciences, 10(11), 773.
Effects of knee flexor submaximal isometric contraction until exhaustion on semitendinosus and biceps femoris long head shear modulus in healthy individuals
Mendes, B., Firmino, T., Oliveira, R., Neto, T., Cruz-Montecinos, C., Cerda, M., … & Freitas, S. R. (2020). Effects of knee flexor submaximal isometric contraction until exhaustion on semitendinosus and biceps femoris long head shear modulus in healthy individuals. Scientific Reports, 10(1), 16433.
Cohesive energy and interaction of superparamagnetic aggregates
Rojas, N., Cerda, M., Ravasio, A., & Rudge, T. (2020). Cohesive energy and interaction of superparamagnetic aggregates. AIP Advances, 10(9), 095019.
Is biceps femoris aponeurosis size an independent risk factor for strain injury?
Freitas, S. R., Abrantes, F., Santos, F., Mascarenhas, V., Oliveira, R., Firmino, T., … & Vaz, J. R. (2020). Is biceps femoris aponeurosis size an independent risk factor for strain injury?. International Journal of Sports Medicine, 41(08), 552-557.
Changes in muscle activity patterns and joint kinematics during gait in hemophilic arthropathy
Cruz-Montecinos, C., Pérez-Alenda, S., Querol, F., Cerda, M., & Maas, H. (2020). Changes in muscle activity patterns and joint kinematics during gait in hemophilic arthropathy. Frontiers in physiology, 10, 1575.
Una mirada a la cultura de datos en Chile – Desafíos y Lecciones de la Pandemia por COVID-19.
Arancibia D, Araos R, Basso L, Bravo L, Guridi J, Härtel S, Jara J, Maass A, Marquet P, Mora S, & Pérez-Acle T. Submesa de Datos Covid-19, MinCiencia.
Eosinophils Control Liver Damage by Modulating Immune Responses Against Fasciola hepática.
Frigerio, S., Da Costa, V., Costa, M., Festari, M. F., Landeira, M., Rodríguez-Zraquia, S. A., … & Freire, T. (2020). Eosinophils Control Liver Damage by Modulating Immune Responses Against Fasciola hepatica. Frontiers in Immunology, 11, 2276.
dSTORM microscopy evidences in HeLa cells clustered and scattered γH2AX nanofoci sensitive to ATM, DNA-PK, and ATR kinase inhibitors.
Liddle, P., Jara-Wilde, J., Lafon-Hughes, L., Castro, I., Härtel, S., & Folle, G. (2020). dSTORM microscopy evidences in HeLa cells clustered and scattered γH2AX nanofoci sensitive to ATM, DNA-PK, and ATR kinase inhibitors. Molecular and Cellular Biochemistry, 473(1), 77-91.
Mathematical Modeling for 2D Light–Sheet Fluorescence Microscopy image reconstruction.
Cueva, E., Courdurier, M., Osses, A., Castañeda, V., Palacios, B., & Härtel, S. (2020). Mathematical modeling for 2D light-sheet fluorescence microscopy image reconstruction. Inverse Problems, 36(7), 075005.
Evaluating Online Consumer Medication Information Systems: Comparative Online Usability Study.
Sigle, S., Barriga, P., Fernández, F. J. C., Juhra, C., Härtel, S., & Fegeler, C. (2020). Evaluating Online Consumer Medication Information Systems: Comparative Online Usability Study. JMIR mHealth and uHealth, 8(6), e16648.
Optimising adjacent membrane segmentation and parameterisation in multi‐cellular aggregates by piecewise active contours.
JARA‐WILDE, J., Castro, I., Lemus, C. G., Palma, K., Valdés, F., Castaneda, V., … & Härtel, S. (2020). Optimising adjacent membrane segmentation and parameterisation in multicellular aggregates by piecewise active contours. Journal of Microscopy, 278(2), 59-75.
Predicting nationwide obesity from food sales using machine learning.
Dunstan, J., Aguirre, M., Bastías, M., Nau, C., Glass, T. A., & Tobar, F. (2020). Predicting nationwide obesity from food sales using machine learning. Health informatics journal, 26(1), 652-663.
Is Banning Texturized Implants to Prevent Breast Implant-Associated Anaplastic Large Cell Lymphoma (BIA-ALCL) a Rational Decision? A Meta-Analysis and Cost-Effectiveness Study
Danilla, S. V., Jara, R. P., Miranda, F., Bencina, F., Aguirre, M., Troncoso, E., … & Albornoz, C. R. (2020). Is banning texturized implants to prevent breast implant-associated anaplastic large cell lymphoma a rational decision? A meta-analysis and cost-effectiveness study. Aesthetic Surgery Journal, 40(7), 721-731.
2019
Chronic Fluoxetine Treatment Induces Maturation-Compatible Changes in the Dendritic Arbor and in Synaptic Responses in the Auditory Cortex
Ampuero, E., Cerda, M., Härtel, S., Rubio, F. J., Massa, S., Cubillos, P., … & Wyneken, U. (2019). Chronic fluoxetine treatment induces maturation-compatible changes in the dendritic arbor and in synaptic responses in the auditory cortex. Frontiers in pharmacology, 10, 804.
Prolonged wait time is associated with increased mortality for Chilean waiting list patients with non-prioritized conditions
Martinez, D. A., Zhang, H., Bastias, M., Feijoo, F., Hinson, J., Martinez, R., … & Prieto, D. (2019). Prolonged wait time is associated with increased mortality for Chilean waiting list patients with non-prioritized conditions. BMC public health, 19(1), 1-11.
Neuromuscular control during gait in people with haemophilic arthropathy
Cruz‐Montecinos, C., Pérez‐Alenda, S., Cerda, M., & Maas, H. (2019). Neuromuscular control during gait in people with haemophilic arthropathy. Haemophilia, 25(2), e69-e77.
Cdh2 coordinates Myosin-II dependent internalisation of the zebrafish neural plate
Araya, C., Häkkinen, H. M., Carcamo, L., Cerda, M., Savy, T., Rookyard, C., … & Clarke, J. D. (2019). Cdh2 coordinates Myosin-II dependent internalisation of the zebrafish neural plate. Scientific Reports, 9(1), 1835.
Does epimuscular myofascial force transmission occur between the human quadriceps muscles in vivo during passive stretching?
Freitas, S. R., Antunes, A., Salmon, P., Mendes, B., Firmino, T., Cruz-Montecinos, C., … & Vaz, J. R. (2019). Does epimuscular myofascial force transmission occur between the human quadriceps muscles in vivo during passive stretching?. Journal of biomechanics, 83, 91-96.
2018
Assessment of tensile mechanical properties of the Achilles tendon in adult patients with haemophilic arthropathy
Cruz Montecinos, C., Pérez-Alenda, S., Contreras-Sepúlveda, F., Querol, F., Cerda, M., & Maas, H. (2019). Assessment of tensile mechanical properties of the Achilles tendon in adult patients with haemophilic arthropathy. Reproducibility study.
Generation of a HER2 Breast Cancer Gold-Standard Using Supervised Learning from Multiple Experts
Chang, V. (2018). Generation of a HER2 breast cancer gold-standard using supervised learning from multiple experts. In Intravascular Imaging and Computer Assisted Stenting and Large-Scale Annotation of Biomedical Data and Expert Label Synthesis: 7th Joint International Workshop, CVII-STENT 2018 and Third International Workshop, LABELS 2018, Held in Conjunction with MICCAI 2018, Granada, Spain, September 16, 2018, Proceedings 3 (pp. 45-54). Springer International Publishing.
A high-speed tracking algorithm for dense granular media
Cerda, M., Navarro, C. A., Silva, J., Waitukaitis, S. R., Mujica, N., & Hitschfeld, N. (2018). A high-speed tracking algorithm for dense granular media. Computer Physics Communications, 227, 8-16.
HER2 Overexpression Segmentation using Machine Learning Classifiers and Quasi-random Patches for Training Data Selection
Raquel Pezoa; Luis Salinas; Claudio Torres; Steffen HärtelApplied Intelligence, submitted
Variable Numbers of Calreticulin Genes in Trypanosoma Cruzi Correlate with Atypical Morphology and Protein Expression
González, A., Härtel, S., Mansilla, J., Sánchez-Valdéz, F., & Ferreira, A. (2018). Variable numbers of calreticulin genes in Trypanosoma cruzi correlate with atypical morphology and protein expression. Immunobiology, 223(12), 802-806.
Evaluating the 2014 sugar-sweetened beverage tax in Chile: An observational study in urban areas
Nakamura, R., Mirelman, A. J., Cuadrado, C., Silva-Illanes, N., Dunstan, J., & Suhrcke, M. (2018). Evaluating the 2014 sugar-sweetened beverage tax in Chile: an observational study in urban areas. PLoS medicine, 15(7), e1002596.
2017
Epigenetic Editing Of The Dlg4/Psd95 Gene Improves Cognition In Aged And Alzheimer’s Disease Mice
Bustos, F. J., Ampuero, E., Jury, N., Aguilar, R., Falahi, F., Toledo, J., … & Van Zundert, B. (2017). Epigenetic editing of the Dlg4/PSD95 gene improves cognition in aged and Alzheimer’s disease mice. Brain, 140(12), 3252-3268.
Interfering of the reelin/ApoER2/PSD95 signaling axis reactivates structural plasticity of mature hippocampal neurons
Ampuero, E., Jury, N., Härtel, S., Marzolo, M. P., & Van Zundert, B. (2017). Interfering of the Reelin/ApoER2/PSD95 signaling axis reactivates dendritogenesis of mature hippocampal neurons. Journal of cellular physiology, 232(5), 1187-1199.
Chile’s National Center for Health Information Systems: A Public-Private Partnership to Foster Health Care Information Interoperability
Capurro, D., Echeverry, A., Figueroa, R., Guiñez, S., Taramasco, C., Galindo, C., … & Härtel, S. (2017). Chile’s National Center for Health Information Systems: a public-private partnership to foster health care information interoperability. In MEDINFO 2017: Precision Healthcare through Informatics (pp. 693-695). IOS Press.
Astrocyte-to-neuron communication through integrin-engaged Thy-1/CBP/Csk/Src complex triggers neurite retraction via the RhoA/ROCK pathway
Maldonado, H., Calderon, C., Burgos-Bravo, F., Kobler, O., Zuschratter, W., Ramirez, O., … & Leyton, L. (2017). Astrocyte-to-neuron communication through integrin-engaged Thy-1/CBP/Csk/Src complex triggers neurite retraction via the RhoA/ROCK pathway. Biochimica et Biophysica Acta (BBA)-Molecular Cell Research, 1864(2), 243-254.
Sleep/wake disorders and the hypocretin/orexin system in a zebrafish model of Parkinson’s Disease
Laliena Izquierdo, A., Castañeda, V., Härtel, S., & Concha Nordemann, M. (2017). Sleep/wake disorders and the hypocretin/orexin system in a zebrafish model of Parkinson’s Disease.
CDK5 downregulation enhances synaptic plasticity
Posada-Duque, R. A., Ramirez, O., Härtel, S., Inestrosa, N. C., Bodaleo, F., González-Billault, C., … & Cardona-Gómez, G. P. (2017). CDK5 downregulation enhances synaptic plasticity. Cellular and Molecular Life Sciences, 74, 153-172.
Light/dark cycles modulate asymmetric parapineal connectivity to the left habenula in zebrafish larvae
Palma González, K., Meynard Moreno, M., Cornejo, V., Cerda Villablanca, M., Jara, J., Härtel, S., & Concha Nordemann, M. (2017). Light/dark cycles modulate asymmetric parapineal connectivity to the left habenula in zebrafish larvae.
Asymmetric morphogenesis of the parapineal organ in the embryonic zebrafish brain
Lemus Cortés, C., Palma, K., Jara, J., Cramer, T., Härtel, S., & Concha Nordemann, M. (2017). Asymmetric morphogenesis of the parapineal organ in the embryonic zebrafish brain.
Extra-embryonic tissue spreading directs early embryo morphogenesis in killifish
Reig, G., Cerda, M., Sepúlveda, N., Flores, D., Castaneda, V., Tada, M., … & Concha, M. L. (2017). Extra-embryonic tissue spreading directs early embryo morphogenesis in killifish. Nature communications, 8(1), 15431.
Automatic classification of human sperm head morphology
Chang, V., Heutte, L., Petitjean, C., Härtel, S., & Hitschfeld, N. (2017). Automatic classification of human sperm head morphology. Computers in biology and medicine, 84, 205-216.
Gold-standard for computer-assisted morphological sperm analysis
Chang, V., Garcia, A., Hitschfeld, N., & Härtel, S. (2017). Gold-standard for computer-assisted morphological sperm analysis. Computers in biology and medicine, 83, 143-150.
Gastrulation in an annual killifish: Molecular and cellular events during germ layer formation in Austrolebias
Pereiro, L., Loosli, F., Fernández, J., Härtel, S., Wittbrodt, J., & Concha, M. L. (2017). Gastrulation in an annual killifish: Molecular and cellular events during germ layer formation in Austrolebias. Developmental Dynamics, 246(11), 812-826.
RyR2-mediated Ca2+ release and mitochondrial ROS generation partake in the synaptic dysfunction cause by amyloid B peptide oligomers. Frontiers in Molecular Neuroscience
SanMartín, C. D., Veloso, P., Adasme, T., Lobos, P., Bruna, B., Galaz, J., … & Paula-Lima, A. C. (2017). RyR2-mediated Ca2+ release and mitochondrial ROS generation partake in the synaptic dysfunction caused by amyloid β peptide oligomers. Frontiers in Molecular Neuroscience, 10, 115.
2016
Ultrasound assessment of fascial connec- tivity in the lower limb during maximal cervical flexion: technical aspects and practical application of automatic tracking
Cruz-Montecinos, C., Cerda, M., Sanzana-Cuche, R., Martín-Martín, J., & Cuesta-Vargas, A. (2016). Ultrasound assessment of fascial connectivity in the lower limb during maximal cervical flexion: technical aspects and practical application of automatic tracking. BMC sports science, medicine and rehabilitation, 8(1), 1-7.
Assessment of Automatically Exported Clinical Data from a Hospital Information System for Clinical Research in Multiple Myeloma
Torres, V., Cerda, M., Knaup, P., & Löpprich, M. (2016, January). Assessment of Automatically Exported Clinical Data from a Hospital Information System for Clinical Research in Multiple Myeloma. In MIE (pp. 332-336).
Segmentation of HER2 protein overexpression in immunohistochemically stained breast cancer images using Support Vector Machines
Pezoa, R., Salinas, L., Torres, C., Härtel, S., Maureira-Fredes, C., & Arce, P. (2016, October). Segmentation of HER2 protein overexpression in immunohistochemically stained breast cancer images using Support Vector Machines. In Journal of Physics: Conference Series (Vol. 762, No. 1, p. 012050). IOP Publishing.
Directional asymmetry in the volume of the human habenula
Ahumada-Galleguillos, P., Lemus, C. G., Díaz, E., Osorio-Reich, M., Härtel, S., & Concha, M. L. (2017). Directional asymmetry in the volume of the human habenula. Brain Structure and Function, 222, 1087-1092.
Leader cells define directionality of trunk, but not cranial, neural crest migration
Richardson, J., Gauert, A., Montecinos, L. B., Fanlo, L., Alhashem, Z. M., Assar, R., … & Linker, C. (2016). Leader cells define directionality of trunk, but not cranial, neural crest cell migration. Cell reports, 15(9), 2076-2088.
Fimbriae have distinguishable roles in Proteus mirabilis biofilm formation
Scavone, P., Iribarnegaray, V., Caetano, A. L., Schlapp, G., Hä rtel, S., & Zunino, P. (2016). Fimbriae have distinguishable roles in Proteus mirabilis biofilm formation. FEMS Pathogens and Disease, 74(5), ftw033.
A frame-based ANN for classification of hyperspectral images: assessment of mechanical damage in mushrooms
Rojas-Moraleda, R., Valous, N. A., Gowen, A., Esquerre, C., Härtel, S., Salinas, L., & O’donnell, C. (2017). A frame-based ANN for classification of hyperspectral images: assessment of mechanical damage in mushrooms. Neural Computing and Applications, 28, 969-981.
2015
In vivo relationship between pelvis motion and deep fascia displacement of the medial gastrocnemius: anatomical and functional implications
Cruz‐Montecinos, C., Gonzalez Blanche, A., Lopez Sanchez, D., Cerda, M., Sanzana‐Cuche, R., & Cuesta‐Vargas, A. (2015). In vivo relationship between pelvis motion and deep fascia displacement of the medial gastrocnemius: anatomical and functional implications. Journal of anatomy, 227(5), 665-672.
Estimation of tensile properties of the Achilles tendon in haemophilic arthropathy of the ankle
Cruz Montecinos, C. V., Pérez Alenda, S., Oyarzún Tejeda, A., Cerda, M., & Querol Fuentes, F. (2015). Estimation of tensile properties of the Achilles tendon in haemophilic arthropathy of the ankle: case study.
Translational cancer research comes of age in Latin America
Investigators of the US–Latin America Cancer Research Network, Llera, A. S., Podhajcer, O. L., Breitenbach, M. M., Santini, L., Muller, B., … & Gross, T. (2015). Translational cancer research comes of age in Latin America. Science Translational Medicine, 7(319), 319fs50-319fs50.
Higher blood vessel density in comparison to the lymphatic vessels in oral squamous cell carcinoma
Maturana-Ramírez, A., Espinoza, I., Reyes, M., Aitken, J. P., Aguayo, F., Hartel, S., & Rojas-Alcayaga, G. (2015). Higher blood vessel density in comparison to the lymphatic vessels in oral squamous cell carcinoma. International Journal of Clinical and Experimental Pathology, 8(10), 13677.
An Implementation of Combined Local-Global Optical Flow
Jara-Wilde, J., Cerda, M., Delpiano, J., & Härtel, S. (2015). An implementation of combined local-global optical flow. Image processing on line, 5, 139-158.
Transactivation activity and nucleocytoplasmic transport of -catenin are independently regulated by its C-terminal end
Maturana, J. L., Niechi, I., Silva, E., Huerta, H., Cataldo, R., Härtel, S., … & Tapia, J. C. (2015). Transactivation activity and nucleocytoplasmic transport of β-catenin are independently regulated by its C-terminal end. Gene, 573(1), 115-122.
Trypanosoma cruzi Infectivity Assessment in ‘in vitro’ Culture Systems by Automated Cell Counting
Liempi, A., Castillo, C., Cerda, M., Droguett, D., Duaso, J., Barahona, K., … & Kemmerling, U. (2015). Trypanosoma cruzi infectivity assessment in “in vitro” culture systems by automated cell counting. Acta tropica, 143, 47-50.
Trypanosoma cruzi Calreticulin Topographical Variations in Parasites Infecting Murine Macrophages
González, A., Valck, C., Sánchez, G., Härtel, S., Mansilla, J., Ramírez, G., … & Ferreira, A. (2015). Trypanosoma cruzi calreticulin topographical variations in parasites infecting murine macrophages.
2014
Bleomycin-induced yH2AX foci map preferentially to replicating domains in CHO9 interphase nuclei
Liddle, P., Lafon-Hughes, L., Di Tomaso, M. V., Reyes-Ábalos, A. L., Jara, J., Cerda, M., … & Folle, G. A. (2014). Bleomycin-induced γH2AX foci map preferentially to replicating domains in CHO9 interphase nuclei. Chromosome research, 22, 463-481.
Gold-standard and improved framework for sperm head segmentation
Chang, V., Saavedra, J. M., Castañeda, V., Sarabia, L., Hitschfeld, N., & Härtel, S. (2014). Gold-standard and improved framework for sperm head segmentation. Computer methods and programs in biomedicine, 117(2), 225-237.
Computational Methods for Analysis of Dynamic Events In Cell Migration
Castañeda, V., Cerda, M., Santibáñez, F., Jara, J., Pulgar, E., Palma, K., … & Hartel, S. (2014). Computational methods for analysis of dynamic events in cell migration. Current Molecular Medicine, 14(2), 291-307.
Spermatozoa from mice deficient in Niemann-Pick disease type C2 (NPC2) protein have defective cholesterol content and reduced in vitro fertilising ability
Busso, D., Oñate-Alvarado, M. J., Balboa, E., Castro, J., Lizama, C., Morales, G., … & Zanlungo, S. (2014). Spermatozoa from mice deficient in Niemann-Pick disease type C2 (NPC2) protein have defective cholesterol content and reduced in vitro fertilising ability. Reproduction, Fertility and Development, 26(4), 609-621.
Ryanodine receptor-mediated Ca2+ release underlies iron-induced mitochondrial fission and stimulates mitochondrial Ca2+ uptake in primary hippocampal neurons
SanMartín, C. D., Paula-Lima, A. C., García, A., Barattini, P., Hartel, S., Núñez, M. T., & Hidalgo, C. (2014). Ryanodine receptor-mediated Ca2+ release underlies iron-induced mitochondrial fission and stimulates mitochondrial Ca2+ uptake in primary hippocampal neurons. Frontiers in molecular neuroscience, 7, 13.
Optimización y paralización de un algoritmo de generación de skeletons
Ivan Rojas, Memoria de Titulo Para Ingeniero Civil en Computación. UF-Med/FCFM, Universidad de Chile, Santiago, Chile.Tutores: Prof. N Hitschfeld, M Cerda and S Härtel
2013
A Comprehensive System for Facial Animation of Generic 3D Head Models driven by Speech
Terissi, L. D., Cerda, M., Gómez, J. C., Hitschfeld-Kahler, N., & Girau, B. (2013). A comprehensive system for facial animation of generic 3D head models driven by speech. EURASIP Journal on Audio, Speech, and Music Processing, 2013, 1-18.
SOFI of GABAB neurotransmitter receptors in hippocampal neurons elucidates intracellular receptor trafficking and assembly. Proceedings of SPIE.
Huss, A., Ramírez, O., Santibáñez, F., Couve, A., Härtel, S., & Enderlein, J. (2013, February). SOFI of GABAB neurotransmitter receptors in hippocampal neurons elucidates intracellular receptor trafficking and assembly. In Single Molecule Spectroscopy and Superresolution Imaging VI (Vol. 8590, pp. 138-144). SPIE.
Stereo Time-of-Flight with Constructive Interference
Castaneda, V., Mateus, D., & Navab, N. (2013). Stereo time-of-flight with constructive interference. IEEE transactions on pattern analysis and machine intelligence, 36(7), 1402-1413.
Daam1 is an effector of asymmetric brain morphogenesis that regulates dendritic and axonal outgrowth in dorsal habenular neurons
Colombo, A., Palma, K., Armijo, L., Mione, M., Signore, I. A., Morales, C., … & Concha, M. L. (2013). Daam1a mediates asymmetric habenular morphogenesis by regulating dendritic and axonal outgrowth. Development, 140(19), 3997-4007.
Asymmetry in neural fields: a spatiotemporal encoding mechanism
Cerda, M., & Girau, B. (2013). Asymmetry in neural fields: a spatiotemporal encoding mechanism. Biological cybernetics, 107, 161-178.
2012
Ciencia Computacional Aplicada a la Biomedicina
Jara J, Histchfeld N, and Härtel S, Further authors : Lemus C, Santibáñez F, Ramirez O, Concha M. Revista BITS de Ciencia, Departamento de Ciencias de la Computacion, Universidad de Chile, Issue 8, pp: 36-43.
TRP, TRPL and cacophony channels mediate Ca2+ influx and exocytosis in axonal terminals of Drosophila photoreceptors
Astorga, G., Härtel, S., Sanhueza, M., & Bacigalupo, J. (2012). TRP, TRPL and cacophony channels mediate Ca2+ influx and exocytosis in photoreceptors axons in Drosophila.
Generación de skeletons a partir de mallas de superficie
Gallardo, L. F. A. (2012). Generación de Skeletons a Partir de Mallas de Superficie (Doctoral dissertation, Universidad de Chile).
Performance of optical flow techniques for motion analysis of fluorescent point signals in confocal microscopy
Delpiano, J., Jara, J., Scheer, J., Ramírez, O. A., Ruiz-del-Solar, J., & Härtel, S. (2012). Performance of optical flow techniques for motion analysis of fluorescent point signals in confocal microscopy. Machine Vision and Applications, 23, 675-689.
Caveolin-1-Enhanced Motility and Focal Adhesion Turnover Require Tyrosine-14 but not Accumulation to the Rear in Metastatic Cancer Cells
Urra, H., Torres, V. A., Ortiz, R. J., Lobos, L., Díaz, M. I., Díaz, N., … & Quest, A. F. (2012). Caveolin-1-enhanced motility and focal adhesion turnover require tyrosine-14 but not accumulation to the rear in metastatic cancer cells. PloS one, 7(4), e33085.
A Method for Analysis of Lipid Vesicle Domain Structure from Confocal Image Data
Husen, P., Fidorra, M., Härtel, S., Bagatolli, L. A., & Ipsen, J. H. (2012). A method for analysis of lipid vesicle domain structure from confocal image data. European Biophysics Journal, 41, 161-175.
2011
Microtubule-associated protein 1B (MAP1B) is required for dendritic spine development and synaptic maturation
Tortosa, E., Montenegro-Venegas, C., Benoist, M., Härtel, S., González-Billault, C., Esteban, J. A., & Avila, J. (2011). Microtubule-associated protein 1B (MAP1B) is required for dendritic spine development and synaptic maturation. Journal of Biological Chemistry, 286(47), 40638-40648.
Development of 3D Architecture of Uropathogenic Proteus mirabilis Batch Culture Biofilms – A Quantitative Confocal Microscopy Approach –
Schlapp, G., Scavone, P., Zunino, P., & Härtel, S. (2011). Development of 3D architecture of uropathogenic Proteus mirabilis batch culture biofilms—A quantitative confocal microscopy approach. Journal of microbiological methods, 87(2), 234-240.
Changes in Rab3D expression and distribution in acini of Sjögren’s Syndrome patients is associated to loss of cell polarity and secretory dysfunction
Bahamondes, V., Albornoz, A., Aguilera, S., Alliende, C., Molina, C., Castro, I., … & González, M. J. (2011). Changes in Rab3D expression and distribution in the acini of Sjögren’s syndrome patients are associated with loss of cell polarity and secretory dysfunction. Arthritis & Rheumatism, 63(10), 3126-3135.
Association of age with sperm DNA fragmentation
Aumento del daño en el DNA espermatico en varones mayores de 40 años.
Horta, F., Madariaga, M., García, A., Hartel, S., & Smith, R. (2011). Association of age with sperm DNA fragmentation. Revista Medica de Chile, 139(3), 306-312.
Location matters: the endoplasmic reticulum and protein trafficking in dendrites.
Ramírez, O. A., Härtel, S., & Couve, A. (2011). Location matters: the endoplasmic reticulum and protein trafficking in dendrites. Biological research, 44(1), 17-23.
High-frequency Field Stimulation of Primary Neurons Enhances Ryanodine Receptor-mediated Ca2+ Release and Generates Hydrogen Peroxide, which Jointly Stimulate NF-kB Activity
Riquelme, D., Alvarez, A., Leal, N., Adasme, T., Espinoza, I., Valdés, J. A., … & Carrasco, M. A. (2011). High-frequency field stimulation of primary neurons enhances ryanodine receptor-mediated Ca2+ release and generates hydrogen peroxide, which jointly stimulate NF-κB activity. Antioxidants & redox signaling, 14(7), 1245-1259.
2010
Confined Displacement Algorithm Determines True and Random Colocalization in Fluorescence Microscopy
Ramirez, O., Garcia, A., Rojas, R., Couve, A., & Härtel, S. (2010). Confined displacement algorithm determines true and random colocalization in fluorescence microscopy. Journal of microscopy, 239(3), 173-183.
The action of sphingomyelinase in lipid monolayers as revealed by microscopic image analysis
Fanani, M. L., Hartel, S., Maggio, B., De Tullio, L., Jara, J., Olmos, F., & Oliveira, R. G. (2010). The action of sphingomyelinase in lipid monolayers as revealed by microscopic image analysis. Biochimica et Biophysica Acta (BBA)-Biomembranes, 1798(7), 1309-1323.
Planar cell polarity signalling regulates cell adhesion properties in progenitors of the zebrafish laterality organ.
Oteiza, P., Köppen, M., Krieg, M., Pulgar, E., Farias, C., Melo, C., … & Concha, M. L. (2010). Planar cell polarity signalling regulates cell adhesion properties in progenitors of the zebrafish laterality organ. Development, 137(20), 3459-3468.
Visualization of inositol 1,4,5-trisphosphate receptors on the nuclear envelope outer membrane by deep etching electron microscopy.
Cárdenas, C., Escobar, M., García, A., Osorio-Reich, M., Härtel, S., Foskett, J. K., & Franzini-Armstrong, C. (2010). Visualization of inositol 1, 4, 5-trisphosphate receptors on the nuclear envelope outer membrane by freeze-drying and rotary shadowing for electron microscopy. Journal of structural biology, 171(3), 372-381.
2009
Lipid domains in giant unilamellar vesicles and their correspondence with equilibrium thermodynamic phases: A quantitative fluorescence microscopy imaging approach.
Fidorra, M., Garcia, A., Ipsen, J. H., Härtel, S., & Bagatolli, L. A. (2009). Lipid domains in giant unilamellar vesicles and their correspondence with equilibrium thermodynamic phases: a quantitative fluorescence microscopy imaging approach. Biochimica et Biophysica Acta (BBA)-Biomembranes, 1788(10), 2142-2149.
Insulin Resistant Skeletal Muscle: Mitochondria Structure, Dynamics And Calcium Homeostasis.
Eisner, V. S., García, A., Härtel, S., Escobar, M., Casas, M., Aedo, P., … & Jaimovich, E. (2009). Insulin Resistant Skeletal Muscle: Mitochondria Structure, Dynamics And Calcium Homeostasis. Biophysical Journal, 96(3), 235a.
Segmentación de Objetos en Imágenes de Microscopia mediante Contornos Activos con Adaptabilidad Topológica.
Olmos Marchant, L. F. (2009). Segmentación de Objetos en Imagénes de Microscopía Mediante Contornos Activos con Adaptabilidad Topológica.
Dendritic Assembly of Heteromeric Gabab Receptor Subunits in Hippocampal Neurons.
Ramirez O, Vidal R, Tello J, Vargas K, Kindler S, Härtel S & A Couve.J Biol Chem. May 8;284(19):13077-85. [Epub 2009 Mar 10] ABSTRACTUnderstanding the mechanisms that control synaptic efficacy through the availability of neurotransmitter…
SMase-induced domain growth and shape relaxation driven by a rate-dependent, out-of-equilibrium, compositional change.
Fanani, M. L., De Tullio, L., Hartel, S., Jara, J., & Maggio, B. (2009). Sphingomyelinase-induced domain shape relaxation driven by out-of-equilibrium changes of composition. Biophysical Journal, 96(1), 67-76.
NADPH Oxidase and Hydrogen Peroxide Mediate Insulin-induced Calcium Increase in Skeletal Muscle Cells.
Espinosa, A., García, A., Härtel, S., Hidalgo, C., & Jaimovich, E. (2009). NADPH oxidase and hydrogen peroxide mediate insulin-induced calcium increase in skeletal muscle cells. Journal of Biological Chemistry, 284(4), 2568-2575.
2008
Changes in mitochondrial dynamics during ceramide-induced cardiomyocyte early apoptosis.
Parra, V., Eisner, V., Chiong, M., Criollo, A., Moraga, F., Garcia, A., … & Lavandero, S. (2008). Changes in mitochondrial dynamics during ceramide-induced cardiomyocyte early apoptosis. Cardiovascular research, 77(2), 387-397.
Exercise and tachycardia increase NADPH oxidase and ryanodine receptor-2 activity: possible role in cardioprotection.
Sánchez, G., Escobar, M., Pedrozo, Z., Macho, P., Domenech, R., Härtel, S., … & Donoso, P. (2008). Exercise and tachycardia increase NADPH oxidase and ryanodine receptor-2 activity: possible role in cardioprotection. Cardiovascular research, 77(2), 380-386.
2007
Marlin-1 and conventional kinesin link GABAB receptors to the cytoskeleton and regulate receptor transport.
Vidal, R. L., Ramírez, O. A., Sandoval, L., Koenig-Robert, R., Härtel, S., & Couve, A. (2007). Marlin-1 and conventional kinesin link GABAB receptors to the cytoskeleton and regulate receptor transport. Molecular and Cellular Neuroscience, 35(3), 501-512.
The initial surface composition and topography modulate sphingomyelinase-driven sphingomyelin to ceramide conversion in lipid monolayers.
De Tullio, L., Maggio, B., Hartel, S., Jara, J., & Fanani, M. L. (2007). The initial surface composition and topography modulate sphingomyelinase-driven sphingomyelin to ceramide conversion in lipid monolayers. Cell biochemistry and biophysics, 47, 169-177.
3D Morpho-Topological Analysis of Asymmetric Neuronal Morphogenesis in Developing Zebrafish. Computational Modelling of Objects Represented in Images. Fundamentals, Methods and Applications.
Härtel, S., Jara, J., Lemus, C. G., & Concha, M. L. (2018). 3D morpho-topological analysis of asymmetric neuronal morphogenesis in developing zebrafish. In Computational modelling of objects represented in images (pp. 215-220). CRC Press.
2006
Contornos activos en tres dimensiones para la segmentación de estructuras biológicas.
Jara, J. F. (2006). Contornos Activos en tres dimensiones para la segmentación y parametrización de estructuras biológicas.
Surface-bound phosphatase activity in ectomycorrhizal fungi: a comparative study between a colorimetric and a microscope-based method.
Alvarez, M., Gieseke, A., Godoy, R., & Härtel, S. (2006). Surface-bound phosphatase activity in ectomycorrhizal fungi: a comparative study between a colorimetric and a microscope-based method. Biology and fertility of soils, 42, 561-568.
ATP steal between cation pumps: a mechanism linking Na+ influx to the onset of necrotic Ca2+ overload.
Castro, J., Ruminot, I., Porras, O. H., Flores, C. M., Hermosilla, T., Verdugo, E., … & Barros, L. F. (2006). ATP steal between cation pumps: a mechanism linking Na+ influx to the onset of necrotic Ca2+ overload. Cell Death & Differentiation, 13(10), 1675-1685.
2005
Shape Transitions and Lattice Structuring of Ceramide-Enriched Domains Generated by Sphingomyelinase in Lipid Monolayers
Härtel, S., Fanani, M. L., & Maggio, B. (2005). Shape transitions and lattice structuring of ceramide-enriched domains generated by sphingomyelinase in lipid monolayers. Biophysical journal, 88(1), 287-304.
Anatomical–physiological determination of surface bound phosphatase activity in ectomycorrhizae of Nothofagus obliqua
Alvarez, M., Godoy, R., Heyser, W., & Härtel, S. (2005). Anatomical–physiological determination of surface bound phosphatase activity in ectomycorrhizae of Nothofagus obliqua. Soil Biology and Biochemistry, 37(1), 125-132.
Di- and triploid erythrocyte identification by multi-parameter image analysis: A new method for the quantification of triploidization rates in rainbow trout (Oncorhynchus mykiss)
Härtel, S., Rojas, R., Räth, C., Guarda, M. I., & Goicoechea, O. (2005). Di-and triploid erythrocyte identification by multi-parameter image analysis: A new method for the quantification of triploidization rates in rainbow trout (Oncorhynchus mykiss). Archivos de Medicina Veterinaria, 37(2), 147-154
2004
Surface-bound phosphatase activity in living hyphae of ectomycorrhizal fungi of Nothofagus obliqua
Alvarez, M., Godoy, R., Heyser, W., & Härtel, S. (2004). Surface-bound phosphatase activity in living hyphae of ectomycorrhizal fungi of Nothofagus obliqua. Mycologia, 96(3), 479-487.
Ultraviolet exposure of thymocytes: selective inhibition of apoptosis
Ojeda, F., Guarda, M. I., Lovengreen, C., Hidalgo, M. A., Folch, H., Härtel, S., & Maldonado, C. (2004). Ultraviolet exposure of thymocytes: selective inhibition of apoptosis. International journal of radiation biology, 80(6), 445-450.
2003
Staurosporine-induced apoptosis in human cornea epithelial cells in vitro
Härtel, S., Zorn‐Kruppa, M., Tykhonova, S., Alajuuma, P., Engelke, M., & Diehl, H. A. (2003). Staurosporine‐induced apoptosis in human cornea epithelial cells in vitro. Cytometry Part A: The Journal of the International Society for Analytical Cytology, 55(1), 15-23.
Ceramide modulates the lipid membrane organization at molecular and supramolecular levels
Carrer, D. C., Härtel, S., Mónaco, H. L., & Maggio, B. (2003). Ceramide modulates the lipid membrane organization at molecular and supramolecular levels. Chemistry and physics of lipids, 122(1-2), 147-152.
NEW PERSPECTIVES ON THE DETERMINATION OF PHOSPHATASE ACTIVITY IN ECTOMYCORRHIZAE OF NOTHOFAGUS OBLIQUA FORESTS IN SOUTHERN CHILE
DE, N. P. E. L. D. (2003). NEW PERSPECTIVES ON THE DETERMINATION OF PHOSPHATASE ACTIVITY IN ECTOMYCORRHIZAE OF NOTHOFAGUS OBLIQUA FOR-ESTS IN SOUTHERN CHILE. Gayana Bot, 60(1), 41-46.
2002
The Susceptibility of Non-UV Fluorescent Membrane Dyes to Dynamical Properties of Lipid Membranes
Härtel, S., Tykhonova, S., Haas, M., & Diehl, H. A. (2002). The susceptibility of non-UV fluorescent membrane dyes to dynamical properties of lipid membranes. Journal of Fluorescence, 12, 465-479.
Bidirectional Control of Sphingomyelinase Activity and Surface Topography in Lipid Monolayers
Fanani, M. L., Härtel, S., Oliveira, R. G., & Maggio, B. (2002). Bidirectional control of sphingomyelinase activity and surface topography in lipid monolayers. Biophysical journal, 83(6), 3416-3424.
Kinetics of apoptotic markers in exogeneously induced apoptosis of EL4 cells
Jessel, R., Haertel, S., Socaciu, C., Tykhonova, S., & Diehl, H. A. (2002). Kinetics of apoptotic markers in exogeneously induced apoptosis of EL4 cells. Journal of cellular and molecular medicine, 6(1), 82-92.
2000
Carotenoids in 1,2-dipalmitoyl-sn- glycero-3-phosphoryl-choline liposomes: incorporation and effects on phase transition and vesicle size
Socaciu, C., Jessel, R., Haertel, S., & Diehl, H. A. (2000). Carotenoids in 1, 2-dipalmitoyl-sn-glycero-3-phosphoryl-choline liposomes: incorporation and effects on phase transition and vesicle size. JOURNAL OF MEDICINE AND BIOCHEMISTRY, 4(2), 71-82.
1998
Methyl-β-Cyclodextrins and Liposomes as Water-Soluble Carriers for Cholesterol Incorporation into Membranes and Its Evaluation by a Microenzymatic Fluorescence Assay and Membrane Fluidity-Sensitive Dyes
Härtel, S., Diehl, H. A., & Ojeda, F. (1998). Methyl-β-cyclodextrins and liposomes as water-soluble carriers for cholesterol incorporation into membranes and its evaluation by a microenzymatic fluorescence assay and membrane fluidity-sensitive dyes. Analytical biochemistry, 258(2), 277-284.
Cholesterol induced variations of membrane dynamics related to the induction of apoptosis in mouse thymocytes
Härtel, S., Ojeda, F., and H, Diehl. (1998). Cholesterol induced variations of membrane dynamics related to the induction of apoptosis in mouse thymocytes. International journal of radiation biology, 74(5), 607-615.
1996
Radiation induced membrane effects in thymocyte apoptosis.
Härtel, S., & Diehl, H. A. (1996). Radiation induced membrane effects in thymocyte apoptosis. Progress in Biophysics and Molecular Biology, (65), 89.